WATSON 349

 

Description:
Oblong white pill indexed with “WATSON 349” on one side, and scored on the other.

Drug Class: Narcotic Analgesic Combinations

Active Ingredients: Acetaminophen / Hydrocodone bitartrate

Strength: 500mg / 5mg

Manufacturer: Watson Laboratories, Inc.

Overview:

Acetaminophen/hydrocodone is a combination of two different pain-relief medicines with two different mechanisms of action.  Hydrocodone works in the brain to change how your body feels and responds to pain. It belongs to a group of medicines called narcotic analgesics (pain medicine) and helps to relieve pain, and stops or prevents cough. Acetaminophen on the other hand is a mild pain reliever and fever reducer at the same time. Due to their different mechanisms of action, Watson 349 is a more potent painkiller than either of the two drugs present in a single pill.

Uses:

 This pill is an effective drug combination that relieves moderate-to-moderately severe pain provided the patient doesn’t overdose. Some of the conditions which it may be useful are:

  • Osteoarthritis of back, knee joints, shoulder joints, wrist joint, ankle joints and other joints
  • Rheumatoid arthritis
  • Joint pains in systemic lupus arthritis, sacro-iliitis and other musculoskeletal disorders
  • Acute back pain/ chronic back pain and neuropathic pains
  • It can also be useful in cancer palliative therapy to control pains of malignancies or cancer.

This medication is best taken at the first sign of pain. If you wait for the pain to worsen, the medication may not work very well.

Dosage:

This drug is available in oral tablet and oral liquid form. It is also available in generic cost-saving versions.

This medicine should be taken exactly as prescribed and only by the person to whom it was prescribed for. Dosage depends on the current medical condition, severity of illness, weight (children), and response to treatment.

Tablet form of this medicine may be taken with or without food. If the patient feels nauseated or vomiting, this medicine can be taken with meals. Liquid form of this medicine should be measured properly not by a regular table spoon but with a calibrated measuring spoon, syringe or cup provided by your health professional.

Missed Dose

Two doses should not be taken at the same time. Take the missed dose as soon as you remember and skip the schedule if it is almost time for the next dose.

Overdose

Immediately call for emergency help with these symptoms: bluish discoloration of the skin, cold and clammy skin, severe drowsiness that may lead to coma, breathing problems, excessive sweating, disturbed functions of cardiovascular system, nausea or vomiting, convulsion/seizures, pain in the abdomen, and bilateral pin point pupils.

Withdrawal Symptoms

This occurs when taking the medicine has been immediately stopped and that it is has been taken regularly and for a longer period of time and with an increased dose. Immediately report to your doctor these symptoms: restlessness, watering eyes, runny nose, nausea, sweating, and muscle aches.

Side Effects:

Common Side Effects

  • anxiety, dizziness, drowsiness
  • mild nausea, vomiting, upset stomach, constipation
  • headache, mood changes
  • blurred vision
  • ringing in your ears
  • dry mouth

Serious Side Effects

  • shallow breathing, slow heartbeat
  • light-headedness, fainting
  • confusion, fear, unusual thoughts or behavior
  • seizure/convulsions
  • urinary problems
  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, yellowing of the skin or eyes

Allergic Symptoms

  • hives
  • difficulty breathing
  • swelling of your face, lips, tongue, or throat

Immediately call the doctor or seek emergency help with severe symptoms and allergic reactions. Some side effects tend to go away as soon as the body has adjusted to treatment; however, report to your doctor if symptoms persist or don’t go away.

Precautions:

Before starting this medicine, it is important to discuss with your doctor the risks and benefits involved in taking this medication. Inform the doctor if you have the following conditions:

  • Brain tumor, head injury, central nervous system disorders
  • Heart, kidney, lung, and liver disease
  • History of drug or substance abuse
  • Alcohol intake of more than three drinks a day
  • Allergy to acetaminophen/hydrocodone, similar medicines, and other substances
  • Pregnant, planning to get pregnant, or breastfeeding
  • If you are taking other medicines (prescription, non-prescription medicines, vitamins, supplements, herbal products)
  • Intestinal or gastric problems
  • If you have had suicidal thoughts or attempted suicide from the past
  • If you plan to undergo other treatments, surgery, or dental extraction

Avoid use of alcohol while taking this medicine. Alcohol increases the risk of liver injury.

Avoid driving or operating machinery. This drug causes you to be dizzy and drowsy.

Caution with use among children and elderly. They are at greater risk of having slow/shallow breathing.

Caution with use among older adults and those with medical conditions and taking other medicines. They are at risk of developing wider side effects.

Inform the doctor if you feel the medicine is not working or if you feel you may be addicted to this medicine.

Storage:

Store this medicine in a safe place, away from others, from children and pets.

Store acetaminophen and hydrocodone at room temperature away from moisture, heat, and direct sunlight.

Discard unused or outdated medicines properly.

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

 

M365 (Acetaminophen and Hydrocodone 325 mg / 5 mg)

M365 is a white, capsule-shaped pill with “M365” indexed on one side. This drug is a mixture of acetaminophen (325mg) and hydrocodone bitartrate (5mg) and belongs to the drug class narcotic analgesics. Both drugs last for a similar length of time in the body which makes them appropriate to be given together. This is a prescribed medicine and both are pain relievers used to treat any pain, back pain, joint pains, arthritis, cough, and many other conditions.

Hydrocodone is an opioid, while acetaminophen is an analgesic. Opioids (narcotics) are very strong pain relievers while analgesics are less potent pain reliever that enhances the effects of hydrocodone and at the same time a fever reducer. Together, they are effective at relieving moderate-to-moderately severe pain.

Dosage 

  • Available in tablet and oral solution.
  • They cost less in generic versions.
  • Dosage is based on weight (children), medical condition, and response to treatment.
  • They work best at the first sign of pain.
  • Not available for use in children 6 years old and below.

Side Effects of Acetaminophen/Hydrocodone

Common side effects

  • Anxiety, drowsiness, and dizziness
  • Some nausea
  • Vomiting
  • Upset stomach
  • Constipation
  • Headache
  • Change in mood
  • Blurry vision
  • Ringing in the ears
  • Dry mouth

Serious side effects that need immediate medical attention

  • Trouble breathing
  • Hives
  • Face, lip, tongue or throat swelling
  • Slow breathing or heartbeat
  • Fainting
  • Confusion
  • Feeling afraid
  • Unwanted thoughts or behavior
  • Seizures
  • Trouble urinating
  • Pain in the upper stomach
  • Itching
  • Not eating
  • Dark urine
  • Clay stools
  • Jaundice of the skin or eyes

Some may people not experience these side effects and some of the common symptoms tend to go away once the body has adjusted to treatment. There are other signs and symptoms not listed above. If they become bothersome or unusual or if the symptoms persist, immediately report to your doctor.

Important Information

Before taking this medicine, inform your treating physician:

  • If you have allergies to acetaminophen or hydrocodone or similar medicines.
  • Tell the doctor if you have allergies to other medicines and other substances.
  • If you have a recent head injury, breathing disorders, liver or kidney disease, low blood pressure, stomach disorders, adrenal gland disorders, mental illness, drug or substance abuse, and curvature of the spine.
  • If you feel you are pregnant, pregnant, or planning to get pregnant.
  • If you are breastfeeding.

How to take this medicine:

  • Take exactly as prescribed. Do not increase or decrease your dosage or use for a longer period without your doctor’s advice.
  • Call emergency help in case of overdose. Symptoms include extreme drowsiness, sweating, pinpoint pupils, nausea, vomiting, dark urine, yellowing of the skin or eyes, confusion, cold and clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, coma, blue lips, shallow breathing, or no breathing.
  • Do not double dose in case of a missed dose. If you are taking the medicine on a regular schedule, take the medicine as soon as you remember and skip the schedule if it is almost time for the next dose.
  • Properly measure liquid form of this medicine provided by the pharmacist. Do not use a regular table spoon.
  • This medicine causes constipation. Exercise, increase fiber in diet and water intake. Do not use laxatives or stool softeners without your doctor’s knowledge.
  • Inform the doctor or the dentist before undergoing other treatment, surgery, or dental extraction that you are taking this medicine.

Storage:

  • Keep out of the reach of children and pets.
  • Store in a safe place away from others. Misuse of this medicine can cause addiction, overdose, toxic side effects, and death.
  • Store acetaminophen and hydrocodone at room temperature away from moisture and heat.
  • Discard properly unused or expired medicines.

 

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

 

M357 (Acetaminophen and Hydrocodone 500 mg / 5 mg)

Hydrocodone/acetaminophen is an inexpensive drug used to treat moderate to severe pain. It is more popular than comparable drugs and is available in multiple generic and brand versions.

It contains hydrocodone, an opioid (narcotic) and acetaminophen, an analgesic (pain reliever and fever reducer). Both drugs are used to reduce pain and work in your brain to block pain signals and decrease one’s ability to feel pain.

This drug is a prescription medication and a controlled substance. It belongs to the drug class narcotic analgesic combinations and is available in oral tablet and oral solution.

ADVANTAGES

  • This drug is available in generic form, and therefore, costs less.
  • A combination of this drug is effective at relieving moderate-to-moderately severe pain.
  • Acetaminophen/hydrocodone combination is more effective than either drug alone.
  • Both drugs last for a similar length of time in the body which makes them appropriate to be given together.

DISADVANTAGES

  • Other generic forms of this drug may not be available in every strength or form as the brand.
  • Excessive doses of acetaminophen can cause liver damage or death.
  • Hydrocodone component of this medicine causes stomach upsets including nausea, vomiting, and constipation; shortness of breath; dizziness; low blood pressure.
  • Unlike NSAID pain relievers (ex. Ibuprofen); acetaminophen does not have any appreciable anti-inflammatory action.
  • This drug is habit-forming and misuse can cause addiction/dependence, overdose and even death.

SIDE EFFECTS

In general, older adults, children, and people with certain medical conditions or people who take other medications are more at risk of developing a wider range of side effects. This medicine is not intended for use in children 6 years old and below for risk of slow or shallow breathing.

Nausea, vomiting, constipation, lightheadedness, dizziness, or drowsiness may occur. Some side effects tend to disappear with regular use of this medicine and some people may not experience these side effects. Consult the doctor if you feel worsening of symptoms or if you feel other side effects not listed in this section.

Seek emergency help with these serious side effects:

  • shallow breathing, slow heartbeat;
  • feeling light-headed, fainting;
  • confusion, fear, unusual thoughts or behavior;
  • seizure (convulsions);
  • problems with urination; or
  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
  • allergic reaction such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Get help in case you experience these overdose symptoms: extreme drowsiness, sweating, pinpoint pupils, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), confusion, cold and clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, coma, blue lips, shallow breathing, or no breathing.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

OTHER PRECAUTIONS

  • Take only as prescribed and as directed. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed.
  • Withdrawal symptoms may be experienced when the medicine has been used for a long time and in high doses. Report to your doctor these symptoms right away.
  • Inform the doctor if you are allergic to acetaminophen/hydrocodone or to other opioids and to other substances.
  • Tell the doctor your medical history and the medicines taken.
  • This drug causes drowsiness and dizziness. Avoid alcohol. Do not drive, operate machineries or do activities that require alertness until you know how this drug affects you.
  • Inform your doctor/dentist about the products you use (including prescription/non-prescription drugs, vitamins, supplements, herbal products, etc.) before undergoing treatment, surgery, or dental extraction.
  • Children and older adults are sensitive to side effects of slow/shallow breathing.
  • Caution with use among elderly due to risk of falls and accidents. This medicine can cause drowsiness, confusion, and dizziness.
  • This medicine can harm the unborn baby. Discuss with your doctor the risks and benefits of this medicine and if you are pregnant, planning to get pregnant, or if you feel that you may be pregnant.
  • Acetaminophen/hydrocodone passes into breast milk. Consult your doctor before breastfeeding.
  • Keep out of the reach of children and pets.
  • Discard unused and expired medicines properly.
  • Store acetaminophen and hydrocodone at room temperature away from moisture and heat.

Pain medications work best when used at the first sign of pain. Discuss with your treating physician the risks and benefits involved in taking this medication. Tell the doctor if the medicine doesn’t seem to work or if the pain persists or worsens.

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

 

M367 (Acetaminophen and Hydrocodone 325 mg / 10 mg)

Acetaminophen/Hydrocodone is a drug combination used to treat back pain; pain; rheumatoid arthritis; cough, and many other conditions. It is indicated for the management of pain severe enough to require opioid analgesic and for which alternative treatments are inadequate.

This pill belongs to the drug class narcotic analgesic combinations and is manufactured by Mallinckrodt Pharmaceuticals. Narcotic analgesics are also called opiates, narcotics or opioid analgesic. It contains one or more other analgesic such as acetaminophen. Acetaminophen is a pain reliever and a fever reducer at the same time which increases effects of hydrocodone, while the latter belongs to a group of narcotic drugs to relieve pain. This combination is more effective than either drug alone. Both drugs last for a similar length of time in the body which makes them appropriate to be given together.

Acetaminophen/Hydrocodone is effective at relieving pain but may however cause dependence and possibility of liver toxicity with too much use of acetaminophen.

IMPORTANT PATIENT INFORMATION

 Misuse, Addiction, and Abuse

This medicine should only be taken by the person to whom it was prescribed for. This should never be given to another person especially to those with history of alcohol or drug abuse. Store in a place where others cannot get to it.

Respiratory Depression

Breathing problems may develop when starting this medicine or when the dose is increased. Recognize the signs and immediately inform the doctor if this happens.

Accidental Ingestion

This medicine should be disposed of properly to avoid accidental ingestion by children which may cause unwanted side effects or even death.

Interaction with other medicines (MAOI, Benzodiazepines, CNS Depressants)

Use of this drug combination with other medicines and alcohol may cause fatal addictive effects or unwanted side effects. Inform the doctor if you are taking other medicines or before undergoing surgery, dental extraction, and other treatments.

Serotonin Syndrome

Signs include: agitation or restlessness, confusion, rapid heart rate and high blood pressure, dilated pupils, loss of muscle coordination or twitching muscles, muscle rigidity, heavy sweating, diarrhea, headache, shivering, and goose bumps. Report to your doctor if you have these symptoms or if you feel anything unusual while taking this medication.

Side Effects

Constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, and abdominal pain may occur. Inform the doctor with worsening symptoms.

Get emergency help if you have trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue, or throat, extreme drowsiness, light-headedness when changing positions, feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.

Some other side effects may not be listed. Discuss with your doctor the risks and benefits of taking this medication or immediately call emergency services with severe or allergic symptoms.

IMPORTANT ADMINISTRATION INSTRUCTION

Dosing

  • This medicine is available in oral and liquid form and cost-saving generic versions.
  • Do not change your dose without doctor’s advice. Take exactly as prescribed.
  • Inform your doctor if the pain doesn’t go away with the dose you are taking or if you feel you have become addicted to this medicine.
  • Do not take more than your prescribed dose. If you miss a dose, take your next dose at your usual time.
  • Immediately call the doctor in case of an overdose (symptoms include extreme drowsiness, sweating, pinpoint pupils, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), confusion, cold and clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, coma, blue lips, shallow breathing, or no breathing).

Pregnancy

Acetaminophen/hydrocodone may be harmful to the unborn child and may cause breathing problems or withdrawal symptoms in newborns. Inform your doctor if you are pregnant or planning to get pregnant or if you feel you are pregnant.

Lactation

This medicine passes through breast milk and may harm the nursing infant. Do not use this medication without first informing your doctor.

Hypotension

Older adults are more sensitive to the effects of this medicine. Caution with use to avoid accident or falls.

Driving or Operating Machinery

Avoid driving or operating machinery or doing activities that involve risk until you know how this medicine affects you.

Constipation

Drink 6 to 8 glasses of full water to prevent constipation and increase fiber in diet. Avoid use of stool softeners or laxatives without first informing your doctor.

Disposal of Unused Medicine

Keep out of the reach of children and pets. Flush unused tablets or dispose of properly.

Storage

Store acetaminophen and hydrocodone at room temperature away from moisture and heat.

 

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

 

S 90 3 (Alprazolam 2 mg)

S 903 is a green, rectangular, pill manufactured by Dava Pharmaceuticals Inc.. This medicine is used to treat anxiety and panic disorders and belongs to the drug class benzodiazepines.

Benzodiazepines work in the central nervous system producing a calming and sedating effect upon administration. They may also be used as a muscle relaxant, during alcohol withdrawal, or before surgery to induce relaxation and amnesia or memory loss. Alprazolam is such a medicine that affects chemicals in the brain which may be unbalanced in some people.

This pill is available in a variety of dosage forms and in less generic forms. When used to help sleep at night, short-acting version is less likely to cause daytime sedation.

Alprazolam is effective at treating anxiety but may cause addiction and severe withdrawal symptoms. Generally, elderly, children, and people with medical conditions are more at risk of developing a wider range of side effects.

Side effects

Drowsiness, slurred speech, lack of balance, memory problems and anxiety in the morning may be experienced. Inform the doctor if symptoms don’t go away.

Seek emergency help as soon as you experience mood or behavioral changes, suicidal thoughts, unusual risk-taking behavior, confusion, hallucination, tremors, involuntary muscle movements, fluttering chest, and heartbeat.

Allergic reactions may occur in rare instances such as hives; difficult breathing; and swelling of your face, lips, tongue, or throat. Immediately call for help with these symptoms.

If you experience other side effects not listed above, immediately call the doctor or seek emergency help right away.

 Precautions

 Inform the doctor if you have allergies to alprazolam or to any similar medicines.

Tell the doctor your medical history, and the medicines being used to avoid drug interaction and unwanted side effects.

This drug causes drowsiness and dizziness. Do not drive or operate machinery while taking this medicine. Use with caution among elderly for risk of accident and falls.

Do not take alcohol or grapefruit while taking this drug to avoid unwanted side effects.

Alprazolam is not recommended for use during pregnancy, when planning to get pregnant, or breastfeeding. It is not approved for use by children below 18 years old.

Immediately call the doctor with these overdose symptoms: extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, light-headedness, and fainting.

Withdrawal symptoms such as blurred vision, insomnia, sweating and seizures may occur when use of this medicine is stopped immediately. Discontinue only with doctor’s advice. Use the medicine as prescribed and follow doctor’s order.

Do not take extra medicine in case of a missed dose. Skip the schedule if it is almost time for the next dose or take the medicine as soon as you remember.

This drug is habit-forming and can be misused. Use by someone to whom this medicine is not prescribed can cause addiction, overdose or even death.

Do not purchase this medicine from the internet. Sale and distribution via internet sales may not be safe for use.

Tips

Extended-release tablets should be taken in the morning, swallowed whole, and not crushed or chewed.

Use a calibrated dropper/syringe or measuring spoon for liquid form of this medicine.

Orally-disintegrating tablets should be placed in the tongue with dry hands and allowed to dissolve not crushed or chewed.

To minimize dizziness or light-headedness, rise slowly from a sitting or lying position.

Store at room temperature away from moisture and heat.

Keep away from children and pets and store in a safe place away from others.

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

m523


Overview:

Acetaminophen/oxycodone is a combination of a narcotic and an analgesic/antipyretic. It works in the brain and nervous system to decrease pain.

Oxycodone is an opioid pain medication while acetaminophen is a less potent drug that enhances the effects of oxycodone. Together, it relieves moderate to severe pain and belongs to the drug class narcotic analgesic combinations.

How to use this medicine: 

  • Take this acetaminophen/oxycodone by mouth with a full glass of water. Do not take laxative or stool softeners without doctor’s advice.
  • Follow the directions on the prescription label. Do not increase or decrease your dosage without consulting your doctor. Do not take more often unless directed.
  • This drug may be taken with or without food. Take with food if it upsets your stomach or if you feel nauseous.
  • Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
  • Don’t keep leftover medicines. You may flush unused/expired medicines in the toilet or mix with cat litter and seal properly before disposal to avoid use by others to whom this medicine is not prescribed.
  • If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
  • Seek emergency help in case of overdose.  Symptoms include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, and fainting.
  • Extended-release pill should be swallowed whole to avoid exposure to fatal dose.
  • Properly measure liquid dose of this medication.

Side Effects:

Constipation, dry mouth, nausea, vomiting, and tiredness may occur. Call the doctor if symptoms persist.

Seek medical help if you are having allergic reactions such as skin rash, itching or hives, swelling of the face, lips, or tongue and if you are experiencing these serious side effects:

  • breathing problems
  • confusion
  • symptoms of liver problems such as dark yellow or brown urine; general ill feeling or flu-like symptoms; light colored stools; loss of appetite, nausea; right upper belly pain; unusually weak or tired; yellowing of skin and eyes
  • signs of low blood pressure like dizziness; feeling faint or light headed; unusual weakness/tiredness, urinary problems
  • redness, blistering, peeling or loosening of the skin, including inside the mouth

All medicines have side effects but with no to little symptoms are experienced by some people. Contact your doctor if you have symptoms not listed above or if you feel unusual or bothered by some effects of this medication.

Warnings:

TOLERANCE may happen if the medicine doesn’t seem to work and would require more doses to relieve pain.

DEPENDENCE or ADDICTION may occur if people are taking it for a long time and feel the need to continuously use the medicine.

WITHDRAWAL SYMPTOMS such as anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping may occur when you immediately stop taking the medicine.

Tell the doctor your medical history, allergies, and medicines taken.

Inform your doctor before taking any other medicines. Some medicines may interact with acetaminophen/oxycodone. Too much acetaminophen can be very dangerous and can cause liver damage.

Acetaminophen/oxycodone may cause dizziness, light-headedness, blurred vision, or drowsiness. Do not drink alcoholic beverages and avoid driving or doing unsafe activities until you know how this medicine affects you.

Consult your doctor before taking any medicines. Inform the doctor and dentist that you are taking this drug before undergoing surgery or dental extraction.

Avoid use of this medicine when pregnant, planning to get pregnant or if you feel you are pregnant. Avoid use when breastfeeding. This medicine can harm the unborn child and the breastfeeding infant.

Caution use among children and elderly. Safety and effectiveness have not been confirmed in children and this medicine can cause accidental falls, breathing problems and drowsiness among elderly.

Storage:

Keep out of children’s reach.

This medicine can be abused. Store in a safe place away from theft, and away from others.

Do not share this medicine. Selling or giving away this drug is dangerous and against the law.

Do not use beyond its expiration date. Dispose properly when no longer in use.

Store in room temperature, away from heat and moisture.

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

 

4839 V

Pill imprint 4839 V has been identified as Acetaminophen-Oxycodone 325 mg /5 mg. It is white, round, and manufactured by Qualitest Pharmaceuticals Inc…

Acetaminophen-Oxycodone 325 mg /5 mg is a pain reliever used to treat moderate to severe pain and belongs to the drug class narcotic analgesic combinations. Narcotic analgesic combinations are products that contain a narcotic analgesic with one or more other analgesics, such as acetaminophen, aspirin, or ibuprofen. They should only be used to treat moderate-to-severe pain when other less potent analgesics are not effective. They are also known as opioids, opioid analgesics, or narcotics and are very effective at relieving pain but may cause addiction, tolerance, and dependence.

DOSAGE

It is available in oral capsule, oral tablet, oral solution, oral tablet, and extended release.

Generally, older adults, children, and people who have certain medical conditions or taking other medications are at risk of developing a wider range of side effects.

SIDE EFFECTS

Symptoms that need to be reported to your doctor or may need immediate medical attention include the following:

  • allergic reactions such as rash, itching or hives, swelling of the face, lips, or tongue
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • breathing/heart problems
  • lightheadedness,
  • confusion, unusual thoughts or behavior;
  • seizure/convulsions
  • urinary problems
  • infertility/menstrual problems
  • sexual problems
  • signs of liver injury such as nausea, upper stomachache, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin/eyes)
  • signs of low cortisol levels such as nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Less common side effects include:

  • constipation
  • dry mouth
  • nausea, vomiting
  • tiredness

Report to your doctor any worsening symptoms or any symptom present but not listed above. Some side effects are rare and would usually go away but if they become unusual or bothersome, call your doctor right away.

IMPORTANT NOTES

  • Excessive doses of acetaminophen may injure the liver or cause death.
  • Serotonin syndrome may result when oxycodone interacts with other medicines.
  • Oxycodone component causes nausea, vomiting, dizziness, constipation and stomach upset.
  • Acetaminophen component does not have an anti-inflammatory effect unlike NSAID pain relievers.
  • Sedation is a side effect that can impair one’s reactions and ability to drive or operate machineries.
  • Alcohol taken with this combined medicine can cause fatal side effects.
  • Acetaminophen and oxycodone can slow or stop breathing.
  • Misuse of this medicine can cause addiction, overdose, and death.
  • This drug can cause withdrawal symptoms in the newborn baby when used during pregnancy.
  • Oxycodone/acetaminophen is not safe to use if you are breastfeeding.
  • Extended-release pill should be swallowed whole to avoid exposure to a potentially fatal dose.
  • Liquid form of this medicine should be measured properly.
  • Never crush or break an acetaminophen and oxycodone pill to inhale the powder or mix it into a liquid to inject the drug into your vein.
  • Store at room temperature away from moisture and heat. Discard expired, leftover, or unused medicines properly.
  • This medicine should be kept away from others (for whom this medicine was not prescribed), to children, and pets.
  • Call emergency help in case of overdose symptoms such as slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, and fainting.

Discuss with your doctor the advantages and disadvantages of taking this medication and how to ease or avoid side effects. Remember to always take this medicine as prescribed and to talk with your treating physician any questions concerning your treatment.

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

 

A333 (Acetaminophen and oxycodone hydrochloride 325 mg / 10 mg)

Description

Oxycodone is a moderately potent opioid (narcotic) analgesic generally indicated for relief of moderate to severe pain. It works in the brain to change how your body feels and responds to pain. Acetaminophen is a less potent pain reliever and fever reducer that increases the effects of oxycodone and works by blocking the effects of a specific enzyme, known as cyclo-oxygenase (COX). This combination medicine helps relieve moderate to severe pain and is under the drug class narcotic analgesic combinations.

Advantages

  • A combination of this medication is more effective than one drug alone.
  • Used for the treatment of moderate-to-moderately severe pain unresponsive to other treatment options.
  • This medication is available in tablet and oral solution forms, extended-release forms, as well as some cost-saving generic versions.

Disadvantages

  • Overdose of acetaminophen component can cause liver injury or death.
  • Oxycodone content of this drug can cause stomach upset, nausea, vomiting, and dizziness.
  • Acetaminophen has no anti-inflammatory action unlike NSAID pain relievers.
  • This medicine is habit-forming and can slow or stop breathing.
  • Misuse can cause addiction, overdose, or death.
  • The baby could become dependent on the drug and can cause withdrawal symptoms to the newborn when taken during pregnancy.
  • Skin redness or rash can occur, which causes blistering and peeling that could be fatal.
  • Dangerous side effects may occur if taken with alcohol.
  • Acetaminophen and oxycodone can pass through breast milk and may harm the nursing baby.
  • This medicine is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
  • Alcohol combined with acetaminophen/oxycodone can lead to serious or fatal side effects.
  • This medicine can impair your thinking and reactions which may affect driving and other activities that require you to be awake and alert.
  • Fatal overdose may result from taking other products together which can cause too much acetaminophen.

Side Effects

Common side effects:

  • headache, drowsiness, tiredness
  • nausea, vomiting, stomach pain, constipation
  • blurred vision
  • dry mouth.

Some of these side effects may decrease with use overtime. Report to your doctor any worsening symptoms. Seek emergency help with symptoms indicated below or for any other effects of this medication not listed.

Serious side effects:

  • shallow breathing, slow heartbeat
  • a light-headed feeling, like you might pass out
  • confusion, unusual thoughts or behavior
  • seizure (convulsions)
  • problems with urination
  • infertility, missed menstrual periods
  • impotence, sexual problems, loss of interest in sex
  • liver problems–nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • low cortisol levels–nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness

Allergic Reactions:

  • hives
  • difficulty breathing
  • swelling of your face, lips, tongue, or throat

Overdose Symptoms:

  • slow breathing and heart rate,
  • severe drowsiness
  • muscle weakness
  • cold and clammy skin
  • pinpoint pupils
  • fainting

Tips

  • Seek emergency help with serious side effects or worsening symptoms.
  • Inform the doctor if the medicine doesn’t seem to work or if you feel you have become addicted to this drug.
  • Do not exceed the prescribed dosage. Follow doctor’s advice and prescription label.
  • Tell the doctor your medical history and medications taken (over-the-counter, herbal products, vitamins, etc.)
  • To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
  • Eat high fiber diet and increase water intake while under treatment.
  • Inform your doctor if you intend to take other medicines or if you need to undergo surgery.
  • Swallow extended-release acetaminophen/oxycodone whole.
  • Do not cut, crush, chew or attempt to dissolve extended-release pill because rapid release and absorption of a potentially fatal dose of oxycodone may occur.
  • Properly measure liquid form of this medicine.
  • Keep in a safe and secure place away from others including pets and children. Properly discard medicines no longer in use.
  • Store at room temperature away from moisture and heat.

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

 

WATSON 3203 (Acetaminophen and hydrocodone bitartrate 325 mg / 7.5 mg)

Acetaminophen/hydrocodone is a combination of two different pain-relief medicines with two different mechanisms of action. Hydrocodone is a narcotic (opioid) pain reliever while acetaminophen (non-opioid pain reliever) is a less potent pain reliever that enhances the effect of hydrocodone. Hydrocodone works in the brain to change how your body feels and responds to pain while acetaminophen also reduces fever.

A combination of this medicine relieves moderate to severe pain such as back pain, pain, rheumatoid arthritis, cough, and many others.

This medicine is white, capsule-shaped with pill imprint “Watson 3203”, and belongs to the drug class narcotic analgesic combinations. Narcotic analgesics are effective at relieving pain, but can cause addiction, dependence, and tolerance when increasing the dosage for maximum pain relieving effect.

Acetaminophen and hydrocodone Side Effects

 Report to your doctor if any of these symptoms worsen:

  • anxiety, dizziness, drowsiness
  • mild nausea, vomiting, upset stomach, constipation;
  • headache, mood changes;
  • blurred vision;
  • ringing in your ears; or
  • dry mouth

To prevent constipation, exercise regularly, increase water intake and fiber in diet. Consult your doctor first with use of laxative and stool softeners as these are stimulants. Rise slowly from a sitting or lying position to minimize dizziness/lightheadedness. Some patients rarely experience side effects and for some, symptoms just disappear having taken the medicine for a period of time.

Discuss with your doctor how to minimize side effects and some other symptoms that may not be present in this list.

Get medical help with allergic reactions such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Tell the doctor right away if you have these serious side effects:

  • shallow breathing, slow heartbeat;
  • feeling light-headed, fainting;
  • confusion, fear, unusual thoughts or behavior;
  • seizure (convulsions);
  • problems with urination; or
  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Acetaminophen/hydrocodone is an effective combination pain relieving medicine; however, use is limited by the dependence potential of the hydrocodone component and the possibility of liver toxicity with excessive doses of acetaminophen.

Important Information

  • Take only as prescribed and as directed. Do not exceed recommended dosage.
  • Acetaminophen and hydrocodone can impair thinking and reactions. Avoid driving or activities that require you to be awake and alert.
  • This drug is not recommended for use by children below 6 years old due to an increased risk of side effect such as slow or shallow breathing.
  • Dosage is based on your medical condition, response to treatment, and weight in children.
  • Pain medications work best if used at the first onset of pain. The medication may not work well if you wait for pain to worsen.
  • Withdrawal symptoms such as restlessness, watering eyes, runny nose, nausea, sweating, and muscle aches may occur. Do not immediately stop taking the medication without advice from your doctor and report these symptoms right away.
  • This drug may not work well if used for a long time, talk with your doctor.
  • Risk for drug-seeking behavior/addiction may be increased with previous alcohol and drug abuse.
  • Inform the doctor the following before taking this medicine:
    • Allergies to acetaminophen and other drugs.
    • Some other allergies
    • Medical history, medications taken and plans of surgery
    • If you are pregnant, planning to get pregnant, or breastfeeding
  • Avoid drinking alcohol. Alcohol may increase your risk of liver damage while taking acetaminophen.
  • Do not double dose in case of a missed dose. Take the medicine as soon as you remember. If the medicine is taken regularly, skip the missed dose if the next dosing schedule is near.
  • Get help with overdose symptoms such as extreme drowsiness, sweating, pinpoint pupils, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), confusion, cold and clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, coma, blue lips, shallow breathing, or no breathing.
  • Hydrocodone is habit-forming, do not distribute, do not share with others and store in a secure place away from others.
  • Keep out of the reach of children and pets.

 There may be other side effects not mentioned in the list. Discuss with your doctor the advantages and disadvantages of taking this medication and how to properly take this medicine.

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

 

 

 

TEVA 833

Generic Name: Clonazepam 1 mg

Description

Teva 833 is a green, round tablet which contains 0.5 mg, 1 mg, or 2 mg clonazepam, a benzodiazepine. Benzodiazepines are psychoactive drugs affecting chemicals in the brain that may be unbalanced in some people. Clonazepam is a seizure medicine, also called an anti-epileptic drug.

Uses

Clonazepam is used to prevent and control seizures. This medication is known as an anticonvulsant or antiepileptic drug and is used in the treatment of benzodiazepine withdrawal; panic disorder; anxiety; sleep paralysis; bipolar disorder, and many more.

How to use Clonazepam

Take clonazepam as prescribed and follow all directions in the prescription label. Do not immediately stop taking this medication or increase/decrease the dosage without doctor’s advice. Do not take more often or for a longer period of time. Conditions may worsen or this can have harmful effects.

Dosage varies with age, weight (children), medical condition, and response to treatment. This medication is usually started a lower dose to minimize side effects.

Withdrawal symptoms such as seizures, mental/mood changes, shaking, stomach/muscle cramps may be experienced if you suddenly stop taking the medication and if it has been taken for a long time. Consult your doctor on proper usage and how to minimize side effects.

This medication rarely causes addiction. There is an increased risk for drug-seeking behavior if you have abused alcohol or drug in the past.

Seizures may worsen at the start of treatment especially if you have different types of seizure disorders. Immediately consult your doctor.

Talk with your doctor if the medication doesn’t seem to work, stops working, or if symptoms persist or worsens.

Side Effects

Common side effects such as drowsiness, dizziness, tiredness, loss of coordination, or increased saliva production may occur. Consult your doctor if condition worsens or if symptoms persist.

Many people do not normally experience serious side effects however, if you experience the following symptoms, immediately report to doctor:

  • new or worsening seizures;
  • severe drowsiness;
  • unusual changes in mood or behavior;
  • confusion, aggression, hallucinations;
  • thoughts of suicide or hurting yourself;
  • weak or shallow breathing;
  • pounding heartbeats or fluttering in your chest; or
  • unusual or involuntary eye movements.

Tell your doctor right away if these rare symptoms occur: confusion, memory problems, signs of depression, suicidal thoughts/attempts, and thoughts about harming yourself.

Seek emergency help with these allergic reactions: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Talk with your doctor about side effects of this medication. Some of the symptoms are not listed above. If you consider them bothersome or unusual, immediately inform your treating physician.

Precautions

Tell your doctor if you are allergic to this medicine or other benzodiazepines if these have been used before. Report also if you have some other types of allergies before taking this medication.

Inform the doctor before taking other medications (prescription/non-prescription drugs, herbal products, medicine, etc.) or undergoing surgery. Some of its ingredients may interact with other medicines which may cause harmful side effects.

Do not drive or operate any machinery or do activities that require alertness. Clonazepam causes drowsiness and dizziness. Caution older adults with use of this medication for risk of falls and accidents.

Clonazepam should only be used when needed. Follow doctor’s advice when taking this tablet during pregnancy. If you plan to get pregnant or feel you may be pregnant, immediately inform the doctor as this may cause harm to both mother and unborn child. This drug may also cause undesirable effects to the nursing infant. Consult your doctor before breastfeeding.

Misusing clonazepam can cause addiction, overdose or death. Keep this medication away from others and avoid selling or giving away as it is against the law.

Store clonazepam at room temperature away from moisture, heat, and light.

Disclaimer:

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.